ACTRN12621000951853尚未招募未知
Pilot Study of Fesability of Neoadjuvant Radiosurgery for Breast Cancer and Non-Small Cell Lung Cancer Intracranial Metastases
St Vincent's Hospital0 个研究点目标入组 10 人开始时间: 2021年7月21日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Histologically confirmed metastatic breast cancer and non-small cell lung cancer
- •New intra-cranial metastases requiring surgical resection for reduction of symptoms or mass effect
- •MRI evidence of 1-4 brain metastases
- •>/= 18 years age
- •Not pregnant or breast feeding
- •No other cancer diagnosis for >5years excluding non-melanomatous skin cancer
- •Willingness to give written informed consent and willingness to participate in and comply with the study.
- •ECOG performance status 0-2
- •Deemed appropriate for surgical management by Neurosurgeon
- •Combined size of all lesions < /=30cm3
排除标准
- •Non-breast or NSCLC histopathology
- •Metastases >4cm max diameter
- •Number of metastases >5
- •Previous whole brain radiotherapy
- •Patients unfit for surgery
- •Patients who have had bevacizumab systemic therapy within the last 6 weeks
- •Any contra-indications to anaesthetic
- •Any contra-indications to MRI
研究者
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