Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section: a Randomized Double-blind Clinical Trial Study
试验速览
- 阶段
- 不适用
- 入组人数
- 87
- 试验地点
- 1
- 主要终点
- morphine consumption
研究概览
简要总结
The purpose of this study is to compare the analgesic effect of ultrasound-guided quadratus lumborum block and iliohypogastric/ilioinguinal nerve block for postoperative pain management in patients undergoing cesarean section.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •singleton pregnancy
- •gestation of at least 37 weeks
- •American Society of Anesthesiologists (ASA) physical status I or II
- •finish Pfannenstiel section under combined spinal and epidural anesthesia
排除标准
- •pruritus existed before the surgery
- •allergic to lidocaine, ropivacaine or dexamethasone
研究组 & 干预措施
quadratus lumborum block
Parturients receive ultrasound-guided quadratus lumborum block as post-operative analgesia.
干预措施: quadratus lumborum block (Procedure)
iliohypogastric/ilioinguinal nerve block
Parturients receive ultrasound-guided iliohypogastric/ilioinguinal nerve block as post-operative analgesia.
干预措施: iliohypogastric/ilioinguinal nerve block (Procedure)
epidural analgesia
Parturients receive epidural morphine via epidural catheter placed during anesthesia as post-operative analgesia.
干预措施: epidural analgesia (Procedure)
结局指标
主要结局
morphine consumption
时间窗: 24 hours postoperatively
Every parturient use a patient-controlled intravenous analgesia pump as supplement for the interventions. The analgesia pump contains morphine and can record morphine consumption. Postoperative use of morphine can reflect analgesic effect.
次要结局
- morphine consumption(48 hours postoperatively)
- effective analgesia time(48 hours postoperatively)
- satisfaction score(48 hours postoperatively)
- hospital stay(at discharge assessed up to 10 days)
- pain score(48 hours postoperatively)
- adverse effect(48 hours postoperatively)
- hospitalize cost(at discharge assessed up to 10 days)
- morphine consumption(6 hours postoperatively)
- morphine consumption(12 hours postoperatively)
- pain score(6 hours postoperatively)
- pain score(12 hours postoperatively)
- pain score(24 hours postoperatively)
- adverse effect(6 hours postoperatively)
- adverse effect(12 hours postoperatively)
- adverse effect(24 hours postoperatively)
研究者
Yi Feng, MD
Head of Anesthesiology
Peking University People's Hospital