Cheese and Human Health

Not Applicable

• Conditions: Cardiovascular Disease
• Interventions: Other: cheese

• Registration Number: NCT01140165
• Lead Sponsor: University of Copenhagen

Brief Summary

The aim of this study is to examine if a diet rich in cheese will have a beneficial effect on risk markers of cardiovascular disease compared to a diet rich in butter.

The primary parameters are total cholesterol as well as LDL-, HDL cholesterol and triacylglycerol (TAG). The secondary parameters are hsCRP, markers of insulin resistance, fasting insulin and glucose (HOMA). Furthermore bloodpressure is measured.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-10
• Study Start: 2010-01
• Primary Completion: 2010-06
• Study First Submitted: 2010-06-04
• Study First Submitted QC: 2010-06-08
• Last Update Submitted: 2010-06-08
• Study First Posted: 2010-06-09
• Last Update Posted: 2010-06-09
• Study Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Sign written consent
• Age: 20-70
• BMI: 20-32
• Refrain from dietary supplements and blood donations prior to, and during the study

Exclusion Criteria

• Known or suspected abuse of alcohol, drugs or medication
• Poor compliance
• Current or previously cardiovascular disease
• Diabetes Mellitus or other severe chronic disease, including severe allergies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
butter	cheese	Danish butter
cheese	cheese	-

Primary Outcome Measures

Name	Time	Method
Total cholesterol	6 weeks
LDL cholesterol	6 weeks
HDL cholesterol	6 weeks
Triglyceride	6 weeks

Secondary Outcome Measures

Name	Time	Method
Blood pressure	6 weeks
Insulin	6 weeks
Glucose	6 weeks
fasting hsCRP	6 weeks

Trial Locations

Locations (1)

Department of Human Nutrition; 🇩🇰 Frederiksberg, Denmark