Effects of long-term treatment with modafinil on relapse and impulse control in alcohol dependence.
Completed
- Conditions
- Alcohol dependent patients and/or polysubstance abusers with alcohol addiction as the primary problem
- Registration Number
- NL-OMON20456
- Lead Sponsor
- - Amsterdam Medical Center; Amsterdam Institute for Addiction Research (AMC; AIAR), - University of Antwerp; Collaborative Antwerp Psychiatric Research Institute (UA; CAPRI)- Psychiatric Centre Alexian Brothers (Boechout; Belgium)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. Current DSM-IV diagnosis of alcohol dependence, but recently detoxified and abstinent and not using benzodiazepines for a least one week;
2. 18-60 years;
Exclusion Criteria
1. Illiteracy - restricted knowledge of Dutch;
2. Mental retardation (IQ < 75);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Test performance (on both neurocognitive tests and self-report questionnaires);<br /><br>2. Craving ratings;<br /><br>3. Relapse (in terms of quantity/frequency measures of alcohol use).<br>
- Secondary Outcome Measures
Name Time Method Improvement or deterioration of specific characteristics (such as depression, ADHD symptoms, anhedonia, fatigue), due to the intervention of modafinil.