Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia
- Conditions
- Anemia, Iron-Deficiency
- Registration Number
- NCT00498511
- Lead Sponsor
- Assaf-Harofeh Medical Center
- Brief Summary
Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia. Due to lack of data on the yield of these endoscopies in young men, they are currently investigated as older men. The aim of this study is to evaluate prospectively the prevalence of various gastrointestinal lesions in young men with iron deficiency anemia. Our hypothesis is that the diagnostic yield of colonoscopy in young anemic men without gastrointestinal symptoms is very low, especially if a potential lesion is detected during upper gastrointestinal endoscopy. Therefore, this study will try to identify predicting factors regarding the yield of both endoscopies. Another purpose is to evaluate the outcome of patients with negative endoscopic results, during a follow-up of two years.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- Not specified
- Men < 40 years old of age with iron deficiency.
- hemoglobin level less than 13 gr/dl documented during the 2 years prior to entering the study with one of the following: 1) iron level less than 45 μg /dl and transferrin saturation less than 10%; 2) ferritin level less than 20 μg/L (both documented during the 4 months prior to entering the study).
- Previously diagnosed disease that explain iron deficiency anemia
- Colonoscopy performed during the last 4 years
- Upper gastrointestinal endoscopy performed during the last 2 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institute of Gastroenterology and Liver Diseases, Assaf harofeh Medical Center
🇮🇱Zerifin, Israel