Clinical investigation of upper gastrointestinal mucosal injury in patients receiving antiplatelet agents as a single agent or in combination: A randomaized control study in healthy volunteers.
Phase 4
- Conditions
- pper gastrointestinal mucosal injury by antiplatelet agents
- Registration Number
- JPRN-UMIN000008311
- Lead Sponsor
- Hyogo College of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- Male
- Target Recruitment
- 32
Inclusion Criteria
Not provided
Exclusion Criteria
a. Presence of diseases with a bleeding tendency b. Previous hypersensitivity for ingredient of aspirin c.Severe comorbidities (including malignant tumor, liver cirrhosis, renal failure, and cardiac failure) d. With no regular use of medicine e.Individuals judged by investigators as ineligible for study enrollment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of upper endoscopic findings (redness, petechia, erosion and ulcer)
- Secondary Outcome Measures
Name Time Method Symptom assessment (using GSRS)