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Clinical trial on the incidence of upper gastrointestinal mucosal injury induced by low-dose aspirin: a randamized control study using transnasal endoscopy in healthy volunteers

Not Applicable
Conditions
upper gastrointestinal mucosal injury
Registration Number
JPRN-UMIN000001375
Lead Sponsor
Endoscopy Center, Tokyo Medical University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up continuing
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

a. hemorrhage tendency b. hypersensitivity for element of aspirin c. previous history of aspirin induced asthma d. previous history of peptic ulcer e. severe blood disease f. severe complication (malignant tumor, liver cirrhosis, renal failure, cardiac failure, etc) g. pregnant woman,or possibility of pregnancy h. smoker i. Inadequate to entry judged by investigators

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The number of transnasal endoscopic findings (red spots, petechiae, erosion, ulcer)
Secondary Outcome Measures
NameTimeMethod
Symptom assessment (using GSRS)
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