Clinical study for the improvement of the onset delay of SSRIs antidepressants by ''Shu-Gan Tiao-Shen'' remedy of Acupuncture

Not Applicable

• Conditions: Moderate Depression; F32.100

• Registration Number: ITMCTR2000003184
• Lead Sponsor: The Second Affiliated Hospital of Guangzhou University of traditional Chinese medicine (Guangdong Hospital of traditional Chinese Medicine)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The scores of HAMD-17 are higher than 17 and less than 24 in the patients who meet the ICD-10 diagnostic criteria of depressive episode and are initially diagnosed as moderate depressive episode;
2. Patients aged 18-55 years;
3. Patients who have no history of serious brain organic diseases and body diseases, and can understand the scale content and cooperate with the treatment;
4. Patients without previous mental history;
5. Right handed patients;
6. Patients who do not drink caffeinated drinks, drink or smoke during the intervention period;
7. Patients with the first moderate depression attack who did not use SSRIs antidepressants or drugs that affect cognitive function within 4 weeks or who stopped using other antidepressants for more than 1 week;
8. Patients who voluntarily participate in clinical research and agree to sign informed consent.

Exclusion Criteria

1. Patients with organic mental disorders or depression related to psychoactive substances and non addictive substances;
2. Patients with other family history of mental illness, such as dementia, schizophrenia, mania, addiction, etc;
3. Patients who have a history of mania or hypomania;
4. Patients who have recently taken drugs that may cause emotional disorders, such as blood benefit equality;
5. Pregnant or lactating women;
6. Patients with vision and hearing impairment.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HAMD-17;

Secondary Outcome Measures

Name	Time	Method
Evaluation of acupuncture expectation;BDI-13;