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Clinical Trials/NCT05088122
NCT05088122
Unknown
Not Applicable

Hormonal Effect Of Different Phases Of Menstrual Cycle On Postural Stability In Postpubertal Females: A Cross Sectional Repeated Measure Design

Cairo University0 sites36 target enrollmentOctober 15, 2021
ConditionsMenstrual Cycle

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Menstrual Cycle
Sponsor
Cairo University
Enrollment
36
Primary Endpoint
Overall stability index
Last Updated
4 years ago

Overview

Brief Summary

High rate of injuries detected during certain periods of menstrual cycle, raised the suggestion of the effecacy of the female sex hormones on soft tissue and neuromuscular control with subsequent deterioration of postural stability and high injury prevalence in post pubertal females so the aim of the present study is to investigate the effect of female sex hormones on postural stability in post pubertal females.

Detailed Description

Thirty-six post pubertal females will participate in this study. They will be selected from students and graduates of Faculty of Physical Therapy, Deraya University and they will be assigned into one group. Postural stability assessment will be carried out throughout three menstrual cycle phases, early follicular, ovulation and mid luteal phases by Biodex balance system. The timing of menstrual cycle phases will be determined by measuring serum estradiol and progesterone level. The exact time of ovulation will be determined by urine lutenizing hormone ovulatory strip test.

Registry
clinicaltrials.gov
Start Date
October 15, 2021
End Date
January 25, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hager Mohey Eldien Abdel Aziz Mahmoud

Demonstrator of physical therapy for women health at deraya university

Cairo University

Eligibility Criteria

Inclusion Criteria

  • All females will be virginal.
  • Their ages will range from 15-25 years.
  • Their body mass index (BMI) will range from 18-27 kg/m
  • All females will have regular menstrual cycle within average of 28 days.

Exclusion Criteria

  • Females having menstrual irregularity.
  • Use of oral contraceptives or any hormonal treatment in the previous six months before participate in this study.
  • History of lower extremity injury, surgery or pain during ADL.
  • Females having any vestibular problems , otitis media, labyrinthitis or any inner ear problems that affect balance.

Outcomes

Primary Outcomes

Overall stability index

Time Frame: two months

Indicator for dynamic postural stability

serum estradiol level

Time Frame: two months

used for accurate timing of menstrual cycle phases, follicular and midluteal.

Anetro-posterior stability index

Time Frame: two months

Indicator for dynamic postural stability

Medio-lateral stability index

Time Frame: two months

Indicator for dynamic postural stability

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