Hormonal Effect of Different Menstrual Phases on Dynamic Balance in Postpubertal Females

• Conditions: Menstrual Cycle
• Interventions: Other: no intervention

• Registration Number: NCT05088122
• Lead Sponsor: Cairo University

Brief Summary

High rate of injuries detected during certain periods of menstrual cycle, raised the suggestion of the effecacy of the female sex hormones on soft tissue and neuromuscular control with subsequent deterioration of postural stability and high injury prevalence in post pubertal females so the aim of the present study is to investigate the effect of female sex hormones on postural stability in post pubertal females.

Detailed Description

Thirty-six post pubertal females will participate in this study. They will be selected from students and graduates of Faculty of Physical Therapy, Deraya University and they will be assigned into one group. Postural stability assessment will be carried out throughout three menstrual cycle phases, early follicular, ovulation and mid luteal phases by Biodex balance system. The timing of menstrual cycle phases will be determined by measuring serum estradiol and progesterone level. The exact time of ovulation will be determined by urine lutenizing hormone ovulatory strip test.

Study Timeline

• Status Verified: 2021-10
• Study First Submitted: 2021-10-08
• Study Start: 2021-10-15
• Study First Submitted QC: 2021-10-20
• Last Update Submitted: 2021-10-20
• Study First Posted: 2021-10-21
• Last Update Posted: 2021-10-21
• Primary Completion: 2021-12-25
• Study Completion: 2022-01-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 36

Inclusion Criteria

1. All females will be virginal.
2. Their ages will range from 15-25 years.
3. Their body mass index (BMI) will range from 18-27 kg/m2.
4. All females will have regular menstrual cycle within average of 28 days.

Exclusion Criteria

1. Females having menstrual irregularity.
2. Use of oral contraceptives or any hormonal treatment in the previous six months before participate in this study.
3. History of lower extremity injury, surgery or pain during ADL.
4. Females having any vestibular problems , otitis media, labyrinthitis or any inner ear problems that affect balance.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
one group	no intervention	-

Primary Outcome Measures

Name	Time	Method
serum estradiol level	two months	used for accurate timing of menstrual cycle phases, follicular and midluteal.
Anetro-posterior stability index	two months	Indicator for dynamic postural stability
Medio-lateral stability index	two months	Indicator for dynamic postural stability
Overall stability index	two months	Indicator for dynamic postural stability