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Berberine and Cinnamon in Management of Diabetes

Not Applicable
Completed
Conditions
Diabetes
Interventions
Other: Placebo (TDS)
Dietary Supplement: Berberine+Cinnamon (TDS)
Registration Number
NCT05570357
Lead Sponsor
National Nutrition and Food Technology Institute
Brief Summary

In this randomized clinical trial, patients with diabetes will be randomly assigned to receive either Berberine, and Cinnamon supplements or placebo for 12 weeks. Then the glycemic characteristics will be compared in two groups.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
44
Inclusion Criteria
  • Age 30-70 years
  • Diagnosed type-2 diabetes mellitus (based on American Diabetes Association criteria)
Exclusion Criteria
  • Patients with an allergy to berberine /cinamon

    • Lactation, pregnancy
    • Patients with any malignancy
    • Patients with unrelated chronic illness
    • Patients with cardiac, liver or respiratory failure

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PlaceboPlacebo (TDS)-
InterventionBerberine+Cinnamon (TDS)-
Primary Outcome Measures
NameTimeMethod
HbA1C0 and 12th week

HbA1C change from baseline

Secondary Outcome Measures
NameTimeMethod
CRP0 and 12th week

measuring the blood concentration of C-reactive protein

Lipid profile0 and 12th week

lipid profiles change from baseline

Anthropometric measurements0 and 12th week

weight, height, BMI, WC

Fasting blood sugar0 and 12th week

Blood sugar change from baseline

Blood Pressure0 and 12th week

measuring according to the BP measurement guideline

Trial Locations

Locations (1)

Azita Hekmatdoost

🇮🇷

Tehran, Middle East, Iran, Islamic Republic of

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