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Clinical Trials/NCT06200298
NCT06200298
Recruiting
Not Applicable

Effectiveness of Erector Spinae Plane Block for Percutaneous Arthrodesis of Spinal Fractures: a Randomized Controlled Trial

University Hospital, Lille1 site in 1 country86 target enrollmentApril 11, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
SPINAL Fracture
Sponsor
University Hospital, Lille
Enrollment
86
Locations
1
Primary Endpoint
Morphine consumption for the first postoperative 24 hours
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

Spinal fracture surgery is a common surgery. Post-operative pain has been reduced by the advent of so-called minimally invasive techniques. The immediate post-operative pain, however, remains relatively high, mainly because of muscle pain following the trauma.

The erector spinae plane block (ESPB) is a loco-regional anesthesia technique first described in 2016.

A retrospective cohort study showed an improvement in post-operative analgesia of percutaneous osteosynthesis spinal surgery through a reduction in 24-hour morphine use.

In order to prove and confirm the effectiveness of this technique, we will conduct a double-blind randomized controlled study.

The objective will be to demonstrate the analgesic effectiveness of the technique by reducing morphine consumption in post-operative. The expected reduction in morphine consumption is set at 30%, based on the clinical experience developed in our practice.

Registry
clinicaltrials.gov
Start Date
April 11, 2024
End Date
July 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University Hospital, Lille
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients with percutaneous arthrodesis spine surgery for fracture
  • Insured persons
  • Age 18 years
  • Being able to receive informed information
  • Have agreed to participate in writing

Exclusion Criteria

  • Minor patient
  • Patient refusal
  • Lack of social security coverage
  • Under guardianship or curatorship
  • Inability to express consent
  • History of spinal surgery
  • Unable to use morphine PCA
  • Contraindication to the use of local morphines and/or anesthetics
  • Contraindication to Loco-Regional Anesthesia
  • Long-term opioid patient (Level II and Level III analgesics)

Outcomes

Primary Outcomes

Morphine consumption for the first postoperative 24 hours

Time Frame: during the first 24H after the procedure

Morphine consumption for the first postoperative 24 hours(mg)

Secondary Outcomes

  • Evolution of postoperative pain(Every 3 hours during the first 24 hours)
  • Evolution of postoperative morphine consumption 6 hours(Post-operative morphic consumption (mg) at 6 hours)
  • Evolution of postoperative morphine consumption 12 hour(Post-operative morphic consumption (mg) at 12 hours)
  • Evolution of postoperative morphine consumption 1 hour(Post-operative morphic consumption (mg) at postoperative 1 hour)
  • Duration of stay in postanesthesia care unit (PACU)(when two consecutives Aldrete scores at 10 occure)
  • intraoperative morphine consumption(during the procedure)
  • Evolution of postoperative morphine consumption 3 hours(Post-operative morphic consumption (mg) at 3 hours)
  • Evolution of postoperative morphine consumption 9 hours(Post-operative morphic consumption (mg) at 9 hours)

Study Sites (1)

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