To compare the bacterial keratitis patients infected with biofilm producing and non biofilm producing bacteria.
Not Applicable
- Conditions
- Health Condition 1: H160- Corneal ulcer
- Registration Number
- CTRI/2022/07/044246
- Lead Sponsor
- Hyderabad Eye Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
The study includes patients of any age or sex diagnosed withculture positive bacterial keratitis
Exclusion Criteria
1 Fungal keratitis
2 Culture negative keratitis
3 Photo keratitis
4 Neurotrophic keratitis
5 Exposure keratitis
6 Inflammatory keratitis like Moorenââ?¬•s ulcer
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method �Proportion of patients with bacterial keratitis infected with biofilm positive and biofilm negative bacteria. <br/ ><br>�Profile of antibiotic resistance in the bacterial isolates positive for biofilm and negative for biofilm. <br/ ><br>�Comparison of the following clinical parameters in patients of bacterial keratitis with biofilm positive and biofilm negative bacteria. <br/ ><br>oRate of corneal ulcer healed <br/ ><br>oVisual acuity <br/ ><br>oRate of patients with worsening despite treatment <br/ ><br>oNeed for surgical intervention <br/ ><br>Timepoint: 1st visit and last visit
- Secondary Outcome Measures
Name Time Method Type of bacteria causing bacterial keratitis will be assessed for, and it would be done based on microbiology report of corneal scrappingTimepoint: 1st visit