EUCTR2008-005432-32-GB进行中（未招募）不适用
Effects of an Angiotensin Receptor Antagonist Candesartan versus a calcium channel blocker Amlodipine on Microvascular Rarefaction, Endothelial Dysfunction and Microalbuminuria in Essential Hypertension
St. George's University of London (SGUL)0 个研究点目标入组 46 人开始时间: 2009年4月16日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 46
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients with uncomplicated mild-to-moderate essential hypertension (sitting diastolic BP = 90 - <110 mmHg and/or systolic BP =140–<180 mmHg) who have not been previously treated for their high blood pressure. Patients age 18-75 years old.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. Malignant or accelerated hypertension.
- •2. Serum creatinine >180 µmol/L
- •3. Ischaemic heart disease
- •4. Cerebrovascular disease
- •5. Impaired liver functions
- •6. Diabetes mellitus
- •7. Pregnancy or risk of pregnancy, or lactation
- •8. History of alcoholism, drug abuse or other problems that are likely to invalidate the informed consent.
- •9. Dark-skinned individuals (capillary microscopy can’t be performed).
研究者
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