The effect of metoclopramide administration to mother on newborn’s bilirubin and mother’s prolactine
- Conditions
- prevention of neonatal jaundice and increasing the volum of breast milk.Neonatal jaundice, unspecified
- Registration Number
- IRCT2016101710324N34
- Lead Sponsor
- Vice chancellor for research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 112
Healthy full-term pregnancy; Mothers with singleton pregnancy; Being Lactating, and having tendency and motivation to breast-feeding; Living in Tabriz; Willingness to continue in the study; -Having at least literacy of reading and writing.
Exclusion criteria: Newborns with birth defects; Newborns that need to neonatal intensive cares; Neonatal jaundice in first day after birth; Neonatal metabolic disease; Taking of hormonal drugs by mothers such as estrogen; Taking of medications that affect the serum prolactin like halopridol, reserpine, mytel- dopa, opiates and cimetidine; Maternal depression; History of previous depression; Inverted nipple; Having absolute or relative contraindication for breast-feeding in the mother including diseases such as untreated TB, infection with HIV, CMV, herpes simplex virus and hepatitis and taking of radioactive drugs and illegal drugs during the breastfeeding period, such as methotrexate, lithium, cyclophosphamide, hydroxyurea, phencyclidine, phenidone, opiate substances and metronidazole; History of chronic disease in the mother
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ewborn’s bilirubin. Timepoint: Before intervention and sixth day after the intervention. Method of measurement: TCB.;Mother’s prolactin serum level. Timepoint: Next day after starting of the intervention and sixth day. Method of measurement: Prolactin ELISA Kit.
- Secondary Outcome Measures
Name Time Method Volume of breast milk. Timepoint: Two hours after the last breastfeeding in the first and sixth day of intervention. Method of measurement: Syringe.;Satisfaction from breastfeeding status. Timepoint: After the end of intervention. Method of measurement: Satisfaction checklist.