The Cardiovascular Benefits of Reducing Personal Exposure to Air Pollution
Not Applicable
Completed
- Conditions
- Blood PressureHeart Rate Variability
- Interventions
- Other: No Face maskDevice: Face mask (Dust Respirator)
- Registration Number
- NCT00809432
- Lead Sponsor
- University of Edinburgh
- Brief Summary
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. The study objectives were to assess the potential cardiovascular benefits of reducing personal particulate air pollution exposure by wearing a facemask in healthy volunteers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
- Healthy volunteers
Exclusion Criteria
- Current smokers
- Significant occupational exposure to air pollution
- Regular medication use (except oral contraceptive pill)
- Intercurrent illness
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Visit 1 No Face mask 2 hour city centre kerbside walk in Beijing China Visit 2 Face mask (Dust Respirator) 2 hour city centre kerbside walk in Beijing China
- Primary Outcome Measures
Name Time Method Ambulatory blood pressure During 24 hour study period
- Secondary Outcome Measures
Name Time Method Heart rate During 24 hour study period Heart rate variability During 24 hour study period Personal air pollution exposure During 2 hour city centre walk
Trial Locations
- Locations (1)
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Medical Union College
🇨🇳Beijing, China