NCT00809432已完成不适用
Beneficial Cardiovascular Effects of Reducing Exposure to Particulate Air Pollution With a Simple Facemask
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Ambulatory blood pressure
研究概览
简要总结
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. The study objectives were to assess the potential cardiovascular benefits of reducing personal particulate air pollution exposure by wearing a facemask in healthy volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers
排除标准
- •Current smokers
- •Significant occupational exposure to air pollution
- •Regular medication use (except oral contraceptive pill)
- •Intercurrent illness
结局指标
主要结局
Ambulatory blood pressure
时间窗: During 24 hour study period
次要结局
- Heart rate(During 24 hour study period)
- Heart rate variability(During 24 hour study period)
- Personal air pollution exposure(During 2 hour city centre walk)
研究者
研究点 (1)
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