Air Pollution and Cardiovascular Disease

Completed

• Conditions: Metabolic Disorder

• Registration Number: NCT02573103
• Lead Sponsor: WeiHuang

Brief Summary

To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-11
• Study First Submitted: 2015-09-28
• Study First Submitted QC: 2015-10-07
• Study First Posted: 2015-10-09
• Primary Completion: 2016-01
• Study Completion: 2016-01
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-10
• Last Update Posted: 2018-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 73

Inclusion Criteria

• without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.

Exclusion Criteria

• Screening visit BP>140/90 mm Hg, fasting glucose >126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dyslipidemia	One year	Analyzed HDL by Beckman AU5800

Secondary Outcome Measures

Name	Time	Method
System oxidative stress	One year	Analyzed oxidative stress biomarkers,such as MDA by HPLC