Comparison of two diagnostic approaches for oral infection analysis - a DIAGORAS pilot study

• Conditions: K02; K05; Dental caries; Gingivitis and periodontal diseases

• Registration Number: DRKS00015623
• Lead Sponsor: Klinik für Präventivzahnmedizin, Parodontologie und Kariologie (PPK)Zentrum für ZahnmedizinUniversität Zürich

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

Healthy patients, subjects with caries lesions and subjects with periodontitis can participate.

Exclusion Criteria

You cannot participate if you smoke more than 10 cigarettes a day, are pregnant or lactating or if you are participating in any other clinical trial within the last 3 months prior to enrolment. You cannot participate either, if you had active periodontal therapy using interventions within the past 3 months.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
quantification of oral bacteria and biomarker (outcome comparison of both methods).<br>Saliva samples will be stored frozen. The analysis with qPCR (Quantitative polymerase chain reaction) will take place in November 2018 (extractions). The analysis with the Diagoras device will be performed in January 2019 after completion of the device development.<br>

Secondary Outcome Measures

Name	Time	Method
The outcome of the device will be correlated to the clinical differentiation of subjects regarding caries, periodontitis or healthy patients.<br>