The effect of platelet rich plasma on MRI findings among patients with knee osteoarthritis

Not Applicable

• Conditions: Knee Osteoarthritis.; Osteoarthritis of knee

• Registration Number: IRCT20211016052782N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Patients with grade 2 or 3 primary osteoarthritis of the knee as determined by the Kellgren and Lawrence criteria (knee pain, morning stiffness less than 30 minutes, crepitus on movement and radiological signs of osteoarthritis include joint space loss, subchondral bone sclerosis and the formation of osteophytes in knee)
Patients aged 50-75 years
Patients who have persistent knee pain for at least six months and with an intensity of at least 4 according to the VAS scale in activities such as going up and down stairs, sitting for long periods and squatting
Patients who are able to walk independently for at least 30 meters
Patients with a body mass index equal to or less than 35
The patient has full consent to participate in the study
The patient has a balanced mental state

Exclusion Criteria

The patient has any contraindications for MRI, including aneurysm clips, pacemakers, metal devices in the body, and claustrophobia
The patient has a history of intra-articular injection in the knee during the last six months
The patient has neuromuscular diseases
The patient has a history of acute traumatic injury to other ligaments and structures of the knee joint with the approval of a specialist
The patient has a history of surgery or previous injury in the knee and other lower limb joints over the last year
The patient has bone implants
The patient has a new fracture in the lower extremities during the last year
The patient has malignant tumors
The patient has participated in exercise therapy and physiotherapy programs during the last three months

Study & Design

• Study Type: interventional
• Study Design: Not specified