Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/CTRI/2024/07/070312
CTRI/2024/07/070312Not yet recruitingNot Applicable

Comparison of Dexmedetomidine and Ondansetron for prevention of post operative nausea and vomiting in laproscopic surgeries

Pt BD Sharma PGIMS, Rohtak1 site in 1 country90 target enrollmentStarted: July 20, 2024Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
90
Locations
1
Primary Endpoint
Comparison of Dexmedetomidine and Ondansetron for prevention of postoperative nausea and vomiting in laparoscopic surgeries.
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The present prospective study will be conducted in the department of anaesthesia and critical care, PGIMS, Rohtak. Written informed consent will be taken from patients included. Comparison of Dexmedetomidine and Ondansetron will be done in Laparoscopic surgeries for prevention of nausea and vomiting. Data will be Compiled and analysed with appropriate statistical test.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • •ASA grade 1 or 2 scheduled for laprocopic surgery under general anaesthesia.

Exclusion Criteria

  • •Refusal to consent History of motion sickness Combined hepatic and renal disease History of Parkinsonism History of vertigo Patient on Chemotherapy ASA grade 3 or more History of GERD Any history of Vomiting.

Outcomes

Primary Outcomes

Comparison of Dexmedetomidine and Ondansetron for prevention of postoperative nausea and vomiting in laparoscopic surgeries.

Time Frame: Post operative nausea and vomiting will be assessed at 0hour,4hour,12hour post surgery

Secondary Outcomes

  • Change in hemodyanamics intraoperatively and in post operative room(Mean Blood Pressure and pulse rate noted at time of induction ,5min,10 min,15 min ,30min,45min,1hr of Surgery and in post operative room)
  • postoperative sedation(at 0 hr,4hr, 12hr post syrgery)

Investigators

Sponsor
Pt BD Sharma PGIMS, Rohtak
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Sanjay Johar

Pt BD Sharma post graduate institute of medical sciences

Study Sites (1)

Loading locations...

Similar Trials

Not yet recruiting
Phase 4
Sedation with two different drugs and postoperative recovery in patients undergoing Endoscopic Retrograde Cholangiopancreatography
CTRI/2024/06/069669M D M Hospital Dr S N Medical College Jodhpur100
Completed
Phase 4
Comparison of drugs Dexmedetomidine and Pentazocine-promethazine in patients undergoing tympanoplasty under sedation
CTRI/2024/03/063761All India Institute of Medical Sciences, Raipur146
Not yet recruiting
Phase 4
Dexmedetomidine versus low molecular weight dextran will be used as adjuvant to Ropivacaine in ultrasound guided erector spinae plane block for postoperative analgesia in patients undergoing Total Abdominal Hysterectomy.
CTRI/2024/11/076412Swami Rama Himalayan University96
Not yet recruiting
Phase 2
Effectiveness of Dexmedetomidine used as an adjuvant with ropivacaine for ultrasound guided supraclavicular brachial plexus block for Upper limb surgery
CTRI/2025/08/092163RNT Medical College90
Recruiting
Phase 3 4
Comparative assessment of dexmedetomidine (analgesic and sedative drug) as a contributory agent to 2 percent plain lignocaine and 2 percent lignocaine with 1:200,000 adrenaline (drug to increase anesthesia time) as local anesthetic agents for removal of impacted lower 3rd molar
CTRI/2025/02/080772subharti dental college40