Effects of HIIT on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.

Not Applicable

Completed

• Conditions: Stroke
• Interventions: Other: High intensity interval training; Other: traditional physical therapy

• Registration Number: NCT06292442
• Lead Sponsor: Riphah International University

Brief Summary

To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-01
• Primary Completion: 2023-10-01
• Study Completion: 2023-11-01
• Study First Submitted: 2024-01-28
• Status Verified: 2024-03
• Study First Submitted QC: 2024-03-04
• Last Update Submitted: 2024-03-04
• Study First Posted: 2024-03-05
• Last Update Posted: 2024-03-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Both males and females were included
• aged 40-60 years
• Chronic stroke patients who experienced a first-ever ischemic stroke
• Stable cardiovascular condition (American Heart Association class B)
• Physician clearance to participate in a 4-week HIIT program
• No prior structured exercise in the last 3 months
• Ability to walk 10 m over ground with or without assistive devices
• Patients who scored >24/30 on MMSE (Mini-Mental State Examination)

Read More

Exclusion Criteria

• Patients who were hospitalized for cardiac or pulmonary disease within the past 3 months
• Patients who had implanted pacemaker or defibrillator
• Patients having conditions where VO2peak assessment is contraindicated, such as uncontrolled hypertension(>180/100), severe aortic stenosis, acute myocarditis, recent myocardial infarction, or other acute cardiovascular events within the past three months, were excluded from the study
• Patients with severe lower limb spasticity (Ashworth Scale scores >2 of 4 for knee flexion, knee extension, or ankle dorsiflexion)
• Pregnant females
• Previous exposure to fast treadmill walking in the past year

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High intensity interval training	High intensity interval training	This group received high-intensity interval training along with conventional treatment for the lower limb muscles
Traditional physical therapy	traditional physical therapy	This group received conventional physical therapy treatment including Range of Motion (ROM) exercises for the affected hip, knee, and ankle joints, as well as stretching exercises for tight lower limb muscles, administered 3 times per week for 4 weeks, with each session lasting approximately 20-30 minutes.

Primary Outcome Measures

Name	Time	Method
Muscle Atrophy	4th week	Measuring tape is used to measure the calf circumference to measure the atrophy, muscle size over time.
Muscle strength	4th week	Manual Muscle Testing is a test that is used to assess muscle strength.
6-Minute Walk Test (6MWT)	4th week	6-Minute Walk Test (6MWT) used to measure Functional capacity, aerobic fitness and endurance.
Aerobic Capacity	4th week	Harvard Step Test is used to measure Functional capacity, aerobic fitness and endurance.

Secondary Outcome Measures

Name	Time	Method
Fastest Gait Speed	4th week	10-Meter Walk Test is a test used for assessing gait speed, monitoring rehabilitation progress, functional assessment, fall risk assessment, and research purposes.

Trial Locations

Locations (1)

Jinnah Hospital, Lahore; 🇵🇰 Lahore, Punjab, Pakistan