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Clinical Trials/NCT06292442
NCT06292442
Completed
Not Applicable

Effects of High-Intensity Interval Training on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.

Riphah International University1 site in 1 country34 target enrollmentSeptember 1, 2023
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ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Riphah International University
Enrollment
34
Locations
1
Primary Endpoint
Muscle Atrophy
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients.

Registry
clinicaltrials.gov
Start Date
September 1, 2023
End Date
November 1, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Both males and females were included
  • •aged 40-60 years
  • •Chronic stroke patients who experienced a first-ever ischemic stroke
  • •Stable cardiovascular condition (American Heart Association class B)
  • •Physician clearance to participate in a 4-week HIIT program
  • •No prior structured exercise in the last 3 months
  • •Ability to walk 10 m over ground with or without assistive devices
  • •Patients who scored \>24/30 on MMSE (Mini-Mental State Examination)

Exclusion Criteria

  • •Patients who were hospitalized for cardiac or pulmonary disease within the past 3 months
  • •Patients who had implanted pacemaker or defibrillator
  • •Patients having conditions where VO2peak assessment is contraindicated, such as uncontrolled hypertension(\>180/100), severe aortic stenosis, acute myocarditis, recent myocardial infarction, or other acute cardiovascular events within the past three months, were excluded from the study
  • •Patients with severe lower limb spasticity (Ashworth Scale scores \>2 of 4 for knee flexion, knee extension, or ankle dorsiflexion)
  • •Pregnant females
  • •Previous exposure to fast treadmill walking in the past year

Outcomes

Primary Outcomes

Muscle Atrophy

Time Frame: 4th week

Measuring tape is used to measure the calf circumference to measure the atrophy, muscle size over time.

Muscle strength

Time Frame: 4th week

Manual Muscle Testing is a test that is used to assess muscle strength.

6-Minute Walk Test (6MWT)

Time Frame: 4th week

6-Minute Walk Test (6MWT) used to measure Functional capacity, aerobic fitness and endurance.

Aerobic Capacity

Time Frame: 4th week

Harvard Step Test is used to measure Functional capacity, aerobic fitness and endurance.

Secondary Outcomes

  • Fastest Gait Speed(4th week)

Study Sites (1)

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