Pilot Trial of Transversus Abdominis Plane Ropivacaine Infusions following Abdominal Surgery

Phase 2

Completed

• Conditions: Analgesia in patients undergoing abdominal surgery; Post-operative analgesia in patients undergoing abdominal surgery; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12608000291381
• Lead Sponsor: Western Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-06-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Age over 18 years
Elective or semi-elective abdominal surgery requiring mid-line incision

Exclusion Criteria

Patient refusal Acute abdomen A clinical history consistent with opioid tolerance including preoperative opioid consumption of longer than one week, intravenous opioid drug use Preoperative use of opioid antagonists like buprenorphine and naltrexone A clinical history of chronic pain, where patients may benefit from early commencement of agents like ketamine Renal impairment with creatinine clearance less than 60 mL/min Drug allergy or contraindication to morphine, ropivacaine, paracetamol Anaesthetist preference for placement of central neuroaxial blockade/catheter Surgeon refusal to placement of catheters Inability of patient to use patient controlled analgesia pump post-operatively or to understand grading of pain via verbal pain score, laparoscopic assisted surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified