The Analgesic Efficacy of Ultrasound-Guided Transversus Abdominis Plane Blocks after Abdominal Surgery

Phase 2

• Conditions: Analgesia in patients undergoing abdominal surgery; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12608000297325
• Lead Sponsor: Dr Elizabeth Hessian

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-06-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

Age over 18 years
Elective or semi-elective abdominal surgery requiring mid-line incision

Exclusion Criteria

Patient refusal
Acute abdomen
A clinical history consistent with opioid tolerance including preoperative opioid consumption of longer than one week, intravenous opioid drug use
Preoperative use of opioid antagonists like buprenorphine and naltrexone
A clinical history of chronic pain, where patients may benefit from early commencement of agents like ketamine
Renal impairment with creatinine clearance less than 60 mL/min
Drug allergy or contraindication to morphine, ropivacaine, paracetamol
Anaesthetist preference for placement of central neuroaxial blockade/catheter
Surgeon refusal to placement of catheters
Inability of patient to use patient controlled analgesia pump post-operatively or to understand grading of pain via verbal pain score

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient controlled analgesia morphine cummulative requirement measured in milligrams of morphine required[48 hours post injection]