Can we protect nerves that carry smell to the brain during brain surgery by measuring the electrical activity? A study to assess the feasibility of such a technique.
Phase 2
- Conditions
- Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system
- Registration Number
- CTRI/2020/01/022920
- Lead Sponsor
- JIPMER Pondicherry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients who are undergoing frontal craniotomy where retraction of the frontal lobe from the base of the brain is likely
Exclusion Criteria
Critically ill patients
Emergency neurosurgical procedures where time cannot be spent to place electrodes
Patients who have already known to have lost olfaction because of previous trauma or surgery or any other condition.
Patients whose clinical status (such as those with impaired consciousness) preclude testing of olfaction before surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method What is the percentage of patients in whom we can successfully measure intraoperative olfactory evoked potential during surgery? <br/ ><br>Timepoint: During the surgical procedure when the testing is going on. (Day one of the trial period)
- Secondary Outcome Measures
Name Time Method What percentage of patients suffer olfactory damage in frontal craniotomies with and without monitoring. <br/ ><br>Timepoint: One assessment during surgery and clinical testing in the post operative period (usually within ten days of surgery)