Development and Validation of an Noninvasive Model for Predicting High Risk Esophageal Varices in Cirrhosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 245
- 试验地点
- 1
- 主要终点
- specificity
研究概览
简要总结
The aim of the study is to develop and validate a new noninvasive method based on routine examination during clinical practice for predicting high risk esophageal varices in cirrhosis.
详细描述
Portal hypertension is the main consequence of cirrhosis. Variceal bleeding is the principal and life-threatening complication of portal hypertension. Endoscopic screening is the golden standard to detect esophageal varices. However, endoscopy is limited by its invasiveness, cost and the discomfort it imposes on patients. With the goal of circumventing these disadvantages, we intend to develop an noninvasive method for predicting high risk esophageal varices.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
specificity
时间窗: through study completion, up to 2 years
the specificity of predicting high risk esophageal varices of the noninvasive model.
Accuracy
时间窗: through study completion, up to 2 years
The golden standard is endoscopic examination.Compare the accuracy of the noninvasive model with the endoscopic examination.
sensitivity
时间窗: through study completion, up to 2 years
the sensitivity of predicting high risk esophageal varices of the noninvasive model.
次要结局
未报告次要终点
研究者
Yanjing Gao
Clinical Professor
Qilu Hospital of Shandong University