Feasibility Study of Vessel Analysis for Noninvasive Diagnosis of Malignancy in Breast Tumors
Not Applicable
Terminated
- Conditions
- Breast Cancer
- Interventions
- Other: Magnetic Resonance Angiography (MRA) of the Breast
- Registration Number
- NCT00630292
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Brief Summary
This is a pilot study designed to explore the feasibility of non-invasively diagnosing the presence of cancer in the breast using non-invasive magnetic resonance imaging (MRI) methods and an analysis of vessel shape defined from these magnetic resonance images.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Female
- Target Recruitment
- 6
Inclusion Criteria
- adult women (age >= 18),
- with Histologically documented newly diagnosed stage II-IV invasive breast cancer appropriate for neoadjuvant (preoperative) systemic therapy.
- ECOG performance status of 0, 1, or 2 at the initiation of the study.
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Exclusion Criteria
- pregnant women
- women with contralateral mastectomies
- known bilateral tumors
- subjects prone to claustrophobia
- contraindicated to have MRI
- mentally impaired
- not fluent in english
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 Magnetic Resonance Angiography (MRA) of the Breast -
- Primary Outcome Measures
Name Time Method Amount of Blood Vessel Tortuosity in Breast With Known Cancer up to two weeks prior to start of chemotheraphy Amount of vessel tortuosity before the start of neoadjuvant chemotherapy and at the end of neoadjuvant chemotherapy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UNC Hospitals
🇺🇸Chapel Hill, North Carolina, United States