Clinical study of the correlation between cholesterol absorption and coronary risk factors or arteriosclerotic diseases, and of the clinical significance of the controlling cholesterol absorption.
Not Applicable
Completed
- Conditions
- Hypercholesterolemia
- Registration Number
- JPRN-UMIN000001718
- Lead Sponsor
- eurology, Respirology, Endocrinology and Metabolism, Miyazaki Medical College, University of Miyazaki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Not provided
Exclusion Criteria
Severe liver or renal dysfunction. The patient using fibrate or insulin. Secondary hypercholesterolemia. Pregnant women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Association between the cholesterol asynthesis/absorption markers before Ezetimibe administration and coronary risk factors or arteriosclerotic diseases. 2. Amount or rate of changes in LDL-C after Ezetimibe administration. 3. Correlation between the amount or rate of changes in LDL-C after Ezetimibe administration and the cholesterol synthesis/absorption markers.
- Secondary Outcome Measures
Name Time Method Changes of RLP-cholesterol, HDL-C, triglyceride, insulin, plasma glucose, HbA1c, and hs-CRP.