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Development and Validation of a Smart Phone Based System to Enhance Gait, Cognition and Socialization in Elderly Fallers

Not Applicable
Conditions
Older Adults
Interventions
Behavioral: Standard of care
Device: Monitoring and training using the system
Registration Number
NCT02769182
Lead Sponsor
Tel-Aviv Sourasky Medical Center
Brief Summary

The main objective of this research is to develop and validate a technology-based solution that addresses the diminished mobility, increased fall risk and impaired cognitive function that are so common among older adults, enabling them to live longer successfully and independently.

Detailed Description

A comprehensive system will be developed to promote mobility, enhance cognitive function, reduce sedentary behavior, increase independence and encourage social inclusion. This novel system will have two distinct yet complementary features: monitoring and treatment that will serve as an "all in one system". The system will consist of wearable sensors and a proprietary developed application. The wearable inertial sensors will measure the acceleration and orientation of the feet during movement. The sensors will feed real-time data to the system, which will process this data using a set of proprietary algorithms enabling continuous monitoring of activity, gait and fall risk, and independence. In addition, designated applications for direct cognitive assessment and training of older adults in their home and community environment will also be used via the Smart phone or mobile tablet. The training, both physical and cognitive, will also include multi-user interactions .Data collected by the system will be processed and integrated to provide comprehensive feedback from multiple domains to the user, caregiver and clinician by way of recommendations and personalized treatment goals.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Ages of 65-85 years
  • History of 1 fall or more in the year prior to the study.
Exclusion Criteria
  • Signs of dementia : Montreal Cognitive Assessment (MoCa) <21 and/or mini mental state examination(MMSE) <24.
  • Psychiatric co-morbidities :major depression as determined by Diagnostic and Statistical Manual of Mental Disorders (DSM) IV criteria
  • Co-existing somatic disorders
  • History of stroke
  • Neurologic disorders that interferes with normal walking (e.g., Parkinson's disease or Alzheimer's disease),
  • Cannot walk without assistance,
  • Severe head trauma or brain tumor,
  • Severe hearing or visual loss (determined by the visual acuity test),
  • Cardio-vascular contradictions (as determined by a physician),
  • Inability to use a Smart phone because of visual and manual impairment or have unstable medical conditions.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standard of careStandard of care-
Monitoring and training using the systemMonitoring and training using the system-
Primary Outcome Measures
NameTimeMethod
Change in average number of steps per dayNumber of steps will be measured during one week after each assessment - at baseline, immediately after the training and 3 months after the training.

This will be evaluated by a small, lightweight waterproof accelerometer placed on the lower back of the participants (Axivity Ltd.)

Changes in the color Trails Making Test part BAt baseline, immediately after the training and 3 months after completing the training.
Secondary Outcome Measures
NameTimeMethod
Changes in gait speedAt baseline, immediately after the training and 3 months after completing the training.

gait speed will be evaluated under two conditions each over 1 minute: i) walking at comfortable speed, ii) walking while performing a cognitive task (dual task).

Changes in fear of fallingAt baseline, immediately after the training and 3 months after completing the training

falls Efficacy Scale International (FES-I).

Changes in enduranceAt baseline, immediately after the training and 3 months after completing the training

Total distance walked in six minutes (6MWT).

Changes in social connectednessAt baseline, immediately after the training and 3 months after completing the training

Social engagement: the Berkman-Syme Social Network Index

Changes in cognitive function: score in Frontal Assessment BatteryAt baseline, immediately after the training and 3 months after completing the training

Frontal Assessment Battery: this battery is sensitive to frontal lobe dysfunction consists of six subtests exploring the following: conceptualization, mental flexibility, motor programming, sensitivity to interference, inhibitory control, and environmental autonomy. It takes approximately 10 minutes to administer.

Changes in functional mobility: dynamic gait index (DGI) scoreAt baseline, immediately after the training and 3 months after completing the training

DGI is a clinical tool to assess gait, balance and fall risk. It evaluates not only usual steady-state walking, but also walking during more challenging tasks

Changes in the Short Form Health SurveyAt baseline, immediately after the training and 3 months after completing the training

The Short Form Health Survey to evaluate different dimensions of health related quality of life including mobility, emotional well-being, and cognitive impairment.

Changes in stride lengthAt baseline, immediately after the training and 3 months after completing the training.

Stride length will be evaluated under two conditions each over 1 minute: i) walking at

Changes in stride and swing time variabilityAt baseline, immediately after the training and 3 months after completing the training.

Stride and swing time variability will be evaluated under two conditions each over 1 minute: i) walking at

Changes in cognitive function: number of digitsAt baseline, immediately after the training and 3 months after completing the training

Working memory (forward and backward digit span): Forward and backward digit span is a common measure of short-term memory (working memory). It is also a component of cognitive ability tests. Backward memory span is a more challenging variation which involves recalling items in reverse order.

Changes in cognitive function: number of correct / incorrect answersAt baseline, immediately after the training and 3 months after completing the training

Dual tasking (DT) walking performance: alternation in the ability to walk while simultaneously performing another task, have been related to gait and balance impairment. The negative effects of DT have been associated with an increased risk of falling, underscoring the clinical importance of DT abilities

Changes in functional mobility: score in Four Square Step TestAt baseline, immediately after the training and 3 months after completing the training

Four Square Step Test is a dynamic balance test that clinically assesses the person's ability to step over objects forward, sideways, and backwards

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