Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria

• Conditions: Retroperitoneal Fibrosis; Idiopathic Aortitis
• Interventions: Other: Establish the clinical, biological and radiological characteristics of patients

• Registration Number: NCT03133949
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological characteristics should make it possible to differentiate them and dismember the Nosological field.

This will be an essential first step before studying prognosis, risk factors, and therapeutic options.

The search for diagnostic criteria on a large series, similar to the study of classification of vascularites of the ACR in 1990, should make it possible to homogenize the diagnoses for the different teams working on the subject, and to begin work Collaborations, which alone can improve patient care in the future.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07-08
• Status Verified: 2017-04
• Study First Submitted: 2017-04-13
• Study First Submitted QC: 2017-04-25
• Last Update Submitted: 2017-04-25
• Study First Posted: 2017-04-28
• Last Update Posted: 2017-04-28
• Primary Completion: 2020-07-08
• Study Completion: 2020-07-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 206

Inclusion Criteria

• Cases :

  • All cases of idiopathic aortitis and retroperitoneal fibrosis followed in participating centers over the past 15 years will be collected.

• Witnesses :

  • Group 1: non-idiopathic inflammatory aortitis: all cases of inflammatory aortitis (apart from idiopathic aortites and isolated retroperitoneal fibrosis) followed in the participating centers over the last 15 years will be collected.
  • Group 2: subjects with noninflammatory aortic disease, atheromatous type or annulo-ectasitic disease, matched by age and sex with cases. This group will be used to define the differential characteristics between idiopathic aortitis and noninflammatory aortic pathology.
  • Group 3: This group will include control subjects aimed at defining radiological normality criteria according to age and sex. As the images are machine-dependent, group 3 controls will be randomly selected from the radiology departments that have performed the scanner or MRI of the corresponding control.

Exclusion Criteria

• Patients under 18 years of age

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
a group of witnesses	Establish the clinical, biological and radiological characteristics of patients	-
Patients with idiopathic inflammatory aortitis	Establish the clinical, biological and radiological characteristics of patients	-

Primary Outcome Measures

Name	Time	Method
Analyze the management of patients with aortic and retroperitoneal fibrosis	1 day

Trial Locations

Locations (1)

CHU Amiens Picardie; 🇫🇷 Amiens, Picardie, France