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Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Multicenter Cohort Study) III

Completed
Conditions
Aortic Dissection
Interventions
Biological: inflammatory response
Registration Number
NCT04918108
Lead Sponsor
Nanjing Medical University
Brief Summary

Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2000
Inclusion Criteria
  • acute type Aortic dissection;
Exclusion Criteria
  • Iatrogenic aortic dissection OR traumatic aortic dissection
  • Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases.
  • Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
inflammatory subphenotypeinflammatory response-
Primary Outcome Measures
NameTimeMethod
30-day mortality30 days after surgery

any cause death within 30 days of surgery

Secondary Outcome Measures
NameTimeMethod
ICU mortality7 days after surgery

any cause death within ICU

Trial Locations

Locations (1)

The first affiliated hospital of nanjing medical university

🇨🇳

Nanjing, Jiangsu, China

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