Comparison Of Ketamine Versus Magesium Sulfate Nebulization For Attenuation Of Postoperative Sore Throat in Patients Undergoing Nasal Surgeries

Phase 1

Not yet recruiting

• Conditions: Chronic sinusitis, unspecified, (2) ICD-10 Condition: J342||Deviated nasal septum,

• Registration Number: CTRI/2020/03/024299
• Lead Sponsor: Department Of Anesthesiology

Brief Summary

This study is for comparison of Ketamine Versus Magnesium Sulfate nebulization For Attenuation Of Postoperative sore throat in a patients undergoing nasal surgeries. Postoperative sore throat is one of the most common adverse effects of General Anesthesia, especially in ENT surgeries. Among the various pharmacological interventions used to reduce its incidence, nebulization has been found to be most effective. Both Ketamine and Magnesium Sulfate decreases the incidence of Postoperative sore throat via NMDA receptor antagonism. Hence in this study, pre operative nebulization with Ketamine or magnesium Sulfate is compared to evaluate the efficacy in decreasing the incidence of postoperative sore throat in patients undergoing ENT-nasal surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-04
• Last Update Posted: 2020-03-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

Elective Nasal Surgeries, American Standard Association Class 1 And 2, Patients with Mallampatti grade 1 and 2.

Exclusion Criteria

Patient refusal, Anticipated difficult airway, Patients with reactive airway disease, Patients with difficult airway who needed more than 3 attempts at intubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Attenuation Of Postoperative Sore Throat	Post extubation: 15 minutes ,30 minutes,1st hour, 2nd hour, 6th hour, 12th hour, 24th hour

Secondary Outcome Measures

Name	Time	Method
Presence of cough Hoarseness of voice	Post extubation: 15 minutes, 30 minutes, 1st hour, 2nd hour, 6th hour, 12th hour, 24th hour

Trial Locations

Locations (1)

Sri Ramachandra Institute Of Higher Education And Research; 🇮🇳 Chennai, TAMIL NADU, India

Sri Ramachandra Institute Of Higher Education And Research

🇮🇳Chennai, TAMIL NADU, India

Sathya priya S

Principal investigator

9952923887

sathya26692@gmail.com