Ketamine Nebulization Versus Magnesium Sulfate Nebulization For Attenuation Of Postoperative Sore Throat In Patients Undergoing Nasal Surgeries- A Prospective Randomised Double Blinded Sudy
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- Attenuation Of Postoperative Sore Throat
研究概览
简要总结
This study is for comparison of Ketamine Versus Magnesium Sulfate nebulization For Attenuation Of Postoperative sore throat in a patients undergoing nasal surgeries. Postoperative sore throat is one of the most common adverse effects of General Anesthesia, especially in ENT surgeries. Among the various pharmacological interventions used to reduce its incidence, nebulization has been found to be most effective. Both Ketamine and Magnesium Sulfate decreases the incidence of Postoperative sore throat via NMDA receptor antagonism. Hence in this study, pre operative nebulization with Ketamine or magnesium Sulfate is compared to evaluate the efficacy in decreasing the incidence of postoperative sore throat in patients undergoing ENT-nasal surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Elective Nasal Surgeries, American Standard Association Class 1 And 2, Patients with Mallampatti grade 1 and 2.
排除标准
- •Patient refusal, Anticipated difficult airway, Patients with reactive airway disease, Patients with difficult airway who needed more than 3 attempts at intubation.
结局指标
主要结局
Attenuation Of Postoperative Sore Throat
时间窗: Post extubation: 15 minutes ,30 minutes,1st hour, 2nd hour, 6th hour, 12th hour, 24th hour
次要结局
- Presence of cough Hoarseness of voice(Post extubation: 15 minutes, 30 minutes, 1st hour, 2nd hour, 6th hour, 12th hour, 24th hour)