Echocardiography Findings and Perioperative Outcomes in Children

Completed

• Conditions: Congenital Cardiac Defect
• Interventions: Diagnostic Test: Echocardiography

• Registration Number: NCT03990779
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study evaluates the association between perioperative echocardiographic Doppler findings and clinical outcomes in pediatric patients undergoing cardiac surgery. In our center, anesthesiologists perform transthoracic or transesophageal echocardiography during perioperative period routinely in children undergoing surgery for congenital cardiac disease. Echocardiographic findings include the doppler patterns of hepatic vein, portal vein, renal artery, renal vein and splenic vein before and after cardiopulmonary bypass. Portal pulsatility index, renal resistive index, and respiratory variations in peak aortic blood flow velocity and diameter of inferior vena cava are measured.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-06-14
• Study First Submitted QC: 2019-06-17
• Study First Posted: 2019-06-19
• Study Start: 2019-06-24
• Primary Completion: 2021-12-30
• Study Completion: 2021-12-30
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-03
• Last Update Posted: 2022-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• All pediatric patients undergoing cardiac surgery

Exclusion Criteria

• Applying extracorporeal membrane oxygenator prior to surgery
• Trouble applying echocardiography

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Children with congenital cardiac disease	Echocardiography	Children with congenital cardiac disease who undergoing surgery

Primary Outcome Measures

Name	Time	Method
Association between Doppler values measured by echocardiography and clinical outcomes after pediatric cardiac surgery	through study completion, an average 1-2 years	To evaluate whether Doppler values of portal vein, hepatic vein, renal artery and vein, and splenic vein measured using echocardiography can predict major adverse outcomes after pediatric cardiac surgery
Characteristics of Doppler values and its derived parameters of portal vein, hepatic vein, renal artery and vein, and splenic vein measured using echocardiography in children with congenital cardiac disease	after anesthetic induction until the end of surgery	To find the characteristics and standard values of Doppler findings measured by echocardiography before and after congenital cardiac surgery

Secondary Outcome Measures

Name	Time	Method
Number of patients with major adverse outcomes after pediatric cardiac surgery	through study completion, an average 1-2 years

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of