ACTRN12613001229763尚未招募不适用
A randomised, double-blind, placebo-controlled trial to assess the effect of niacinamide on levels of Fibroblast Growth factor 23 (FGF23) in patients with chronic kidney disease stages 3b-4.
Christopher Hood0 个研究点目标入组 90 人开始时间: 2013年11月8日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Patients with Chronic Kidney Disease (CKD) Stages 3b-4 (eGFR between 15-45ml/ min/1.73m2)
排除标准
- •1. Patients with a history of psychological illness or condition which interferes with their ability to understand or comply with the requirements of the study
- •2. Medical conditions that impact on phosphate metabolism (apart from CKD), eg. primary hyperparathyroidism or hypoparathyroidism; previous subtotal parathyroidectomy; gastrointestinal malabsorption disorders such as Crohn’s disease, ulcerative colitis, coeliac disease or severe liver dysfunction
- •3. Treatment with any drug that could impact on mineral metabolism
- •4. Treatment with anti-epileptic drugs
- •5. Treatment with anticoagulants
- •6. Renal transplantation
- •7. Rapid changes of residual renal function
- •8. Serum PTH greater than 50 pmol/L
- •9. Serum albumin less than 30g/L
- •10. Active malignancy
- •11. Pregnancy or breast feeding
研究者
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