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Clinical Trials/NCT06091202
NCT06091202
Recruiting
Phase 3

Tele-Collaborative Outreach to Rural Patients With Chronic Pain: The CORPs Trial

Oregon Health and Science University4 sites in 1 country608 target enrollmentJuly 11, 2024
ConditionsChronic Pain

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Chronic Pain
Sponsor
Oregon Health and Science University
Enrollment
608
Locations
4
Primary Endpoint
Pain Interference - Brief Pain Inventory (BPI)
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

This is a randomized controlled trial comparing the effectiveness of a remotely delivered collaborative care intervention for chronic pain versus a minimally enhanced control group. The specific aims of the study are: (1) compare the effectiveness of tele-collaborative pain care vs. minimally enhanced usual care to improve pain interference over 12 months of follow-up, and (2) oversample women and rural veterans of minoritized race/ethnicity to test heterogeneity of treatment effects across birth sex and race/ethnicity.

Detailed Description

The CORPs trial is a multisite pragmatic effectiveness trial taking place at four geographically diverse VA sites. The CORPs trial will assess the effectiveness of a nurse-led tele-collaborative pain care intervention (CORPs) compared to a one-time education session with a nurse (minimally enhanced usual care, or MEUC) at improving pain and health outcomes for Veterans living in rural areas. This study focuses on management of pain with non-medication services and therapies. Veterans who enroll will participate for 12-months and will be randomized to one of 2 groups: 1) CORPs (with access to a nurse by phone/video for the duration of the study), or 2) One-time education session with the nurse by phone/video to review resources for pain. All participants complete research assessments at the start of the study, and at 3-, 6-, 9-, and 12-months by phone.

Registry
clinicaltrials.gov
Start Date
July 11, 2024
End Date
June 1, 2027
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Travis Lovejoy

Principal Investigator

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

  • U.S. Veteran
  • Rural Residence based on Rural Urban Commuting Area codes
  • High Impact Chronic pain, determined through a phone screening
  • Access to landline or cell phone
  • English Speaking

Exclusion Criteria

  • Cognitive impairment that would impact participation in the study
  • Plans to move in the next 3 months
  • Surgery in the past 3 months
  • In long-term inpatient or hospice care
  • Terminal illness (defined as life expectancy of less than 12 months)
  • Active participation in another pain intervention study

Outcomes

Primary Outcomes

Pain Interference - Brief Pain Inventory (BPI)

Time Frame: Baseline, 3-, 6-, 9-, and 12 Months

Pain Interference subscale from the Brief Pain Inventory. Scores are reported on a range of 0 - 10, with higher scores indicating more impairment due to pain.

Secondary Outcomes

  • Quality of Life - Veterans RAND-12 (VR-12)(Baseline, 3-, 6-, 9-, and 12 Months)
  • Quality of Sleep - PROMIS Sleep Disturbance Scale(Baseline, 3-, 6-, 9-, and 12 Months)
  • Physical Functioning - PROMIS Physical Functioning Scale(Baseline, 3-, 6-, 9-, and 12 Months)
  • Anxiety Symptoms - Generalized Anxiety Disorder-7 (GAD-7)(Baseline, 3-, 6-, 9-, and 12 Months)
  • Engagement in Non-Pharmacological Services/Treatments - Nonpharmacological Self-Care Approaches survey (NSCAP)(Baseline, 3-, 6-, 9-, and 12 Months)
  • Pain Intensity - Brief Pain Inventory (BPI)(Baseline, 3-, 6-, 9-, and 12 Months)
  • Depressive Symptoms - Patient Health Questionnaire-9 (PHQ-9)(Baseline, 3-, 6-, 9-, and 12 Months)
  • Suicidal Behavior - Electronic Health Record (EHR)(Baseline, 3-, 6-, 9-, and 12 Months)

Study Sites (4)

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