NCT03586492已完成不适用
SPECT Myocardial Perfusion Reserve Using a Cadmium Zinc Telluride (CZT) Camera in Cardiovascular Risk Stratification and Ischemia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 137
- 试验地点
- 4
- 主要终点
- Regional and global CFR
研究概览
简要总结
CFR has been studied for few years using 82 Rubidium PET (positron emission tomography) /CT. CFR has shown to be correlated with cardiovascular events occurring in the 10 following years. CFR also helps to identify multivessel coronary disease. Few studies have shown the possibility to calculate CFR during myocardial perfusion SPECT on new ultrafast CZT cameras.
详细描述
Evaluate the contribution of CZT SPECT CFR in cardiovascular risk stratification: correlation with clinical scores, with calcium score, and when pathological with coronarography findings especially fractional flow reserve (FFR).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred for myocardial ischemia screening
排除标准
- •Patient already suffering from coronary disease with angioplasty, bypass surgery or myocardial infarction.
- •Contraindications related to the stress test:
- •Acute Coronary Syndrome <5 days Unstable angina Stenosis of left main artery untreated Uncontrolled severe rhythm disorders Uncontrolled heart failure
- •Contraindications to dipyridamole and regadenoson:
- •Hypotension (systolic <90mmHg) Severe pulmonary arterial hypertension Bradycardia <40 beats / minute Sinusal Dysfunction and 2nd or 3rd degree Atrioventricular block Decompensated Heart Failure with Ejection Fraction <25% Stenosis of supra-aortic trunks unilateral> 70% or bilateral> 50% Dipyridamole and regadenoson allergy
- •Patients with pacemaker, or who have had valvular surgery,
- •Well-known dilated cardiopathy
- •Pregnant or breastfeeding women,
- •Minor people
- •Persons under guardianship or under guardianship
结局指标
主要结局
Regional and global CFR
时间窗: Day 0
Regional and global CFR calculated from CZT SPECT myocardial perfusion: correlation with clinical score and calcium score
次要结局
- FFR Regional CFR after one year of medical treatment(Up to one year)
研究者
研究点 (4)
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