Investigation into the use of radiofrequency ablation for the treatment of watermelon stomach
Not Applicable
Completed
- Conditions
- Gastric antral vascular ectasia (GAVE)Circulatory System
- Registration Number
- ISRCTN13565602
- Lead Sponsor
- niversity College London
- Brief Summary
2019 results in https://pubmed.ncbi.nlm.nih.gov/31080606/ (added 07/09/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Existing diagnosis of GAVE that has resulted in anaemia requiring either intravenous iron replacement or blood transfusion
2. Undergoing endoscopic treatment with RFA
3. Aged 18 years and over
Exclusion Criteria
1. Active malignancy
2. Anaemia due to other cause such as coeliac disease, small bowel pathology or haematological disease
3. Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Quality of life is measured using the Functional Assessment of Chronic Illness Therapy - fatigue scale (FACIT-F) questionnaire at baseline (pre-RFA) and 6 months post-RFA<br> 2. Number of red blood cell (RBC) packs transfused (transfusion requirement), parenteral iron requirements and haemoglobin concentrations (g/dL) are measured by reviewing patient notes and blood tests at baseline (pre-RFA) and 6 months post-RFA<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Number of endoscopy treatment sessions are measured by reviewing patient notes at baseline (pre-RFA) and 6 months post-RFA<br> 2. Percentage surface regression in macroscopically evident GAVE is measured during endoscopy at any follow up endoscopy in the 6 months post-treatment<br>