A national patient registry for radiofrequency ablation (RFA) for Barrett's oesophagus

Not Applicable

• Conditions: Oesophageal Cancer/ Barrett's Oesophagus; Cancer; Malignant neoplasm of oesophagus

• Registration Number: ISRCTN93069556
• Lead Sponsor: Joint UCLH/UCL Biomedical Research Unit (UK)

Brief Summary

2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25539672 2021 results in https://pubmed.ncbi.nlm.nih.gov/33547491/ (added 08/02/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-06-14
• Last Update Posted: 22 February 2021
• Study Completion: 2028-03-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Patients will be recruited from those referred for ablative management of Barrett's oesopahgus or squamous dysplasia with HALO RFA
2. Patients must have no contraindications to endoscopy
3. Males and non-pregnant females over the age of 21 years. Female patients who are pre-menopausal must practice a medically acceptable form of contraception.
4. Patients must sign an informed consent form

Exclusion Criteria

1. Presence of invasive carcinoma of the oesophagus
2. Patients in whom endoscopy is contraindicated
3. Patients with oesophageal varices
4. Previous radiotherapy
5. Patients who have undergone Hellers myotomy
6. Pregnant females
7. People under the age of 21 years

Study & Design

• Study Type: Observational
• Study Design: Not specified