Detection of buried Barrett glands after Radiofrequency Ablation (RFA) with Volumetric Laser Endomicroscopy (VLE); a histopathology correlation study
Recruiting
- Conditions
- Barrett's esophagusBuried Barrett'sBarrett slokdarm
- Registration Number
- NL-OMON24516
- Lead Sponsor
- AMC Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1. Age > 18 – 80 years;
2. Patients post RFA treatment with 100% endoscopic regression of Barrett’s epithelium;
Exclusion Criteria
1. Presence of significant stenosis;
2. Presence of erosive esophagitis;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Presence of structures suggesting BB on VLE; <br /><br>2. VLE characteristics of buried glands (e.g. sparsely distributed hyposcattering structures underneath NSE with various sizes and shapes) ;<br /><br> - Number of glands;<br /><br> - Size of glands ;<br /><br> - Location of glands from GEJ;<br /> <br> - Depth level of glands <br /><br>3.Presence of structures suggesting of BB in ER specimens and, if present:<br /> <br> - Number of glands <br /><br> - Size of glands <br /><br> - Location of glands from GEJ <br /><br> - Depth level of glands <br>4. Histology: Intestinal metaplasia, Dysplasia Correlation of OFDI images with corresponding histology of ER specimen
- Secondary Outcome Measures
Name Time Method