Resistance Exercise, Metabolism and Time of Day
- Conditions
- Metabolic Disease
- Interventions
- Behavioral: Exercise training
- Registration Number
- NCT05321914
- Lead Sponsor
- University of Glasgow
- Brief Summary
The aim of the current study is to determine the effect of time of day on the muscle and metabolic responses to resistance exercises in obese or overweight adults. To achieve this aim we have the following objectives:
1. Compare the effects of resistance exercise training performed in the morning vs the evening on insulin sensitivity
2. Compare the effects of resistance exercise training performed in the morning vs the evening on gains in muscle mass and strength
3. Compare the acute glucose responses to resistance exercise performed in the morning vs the evening
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
- pass the physical activity readiness questionnaire
- body mass index (BMI) >27kg/m² and limited to 40 kg/m².
- Prior surgery for weight loss
- Prior history of heart, lung, cancer, endocrine or liver disease
- Participating in more than 1 hour structured exercise training per week
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Morning exercise Exercise training Exercise training in the morning (6:00-10:00am) Evening exercise Exercise training Exercise training in the evening (4:00-8:00pm)
- Primary Outcome Measures
Name Time Method Change in insulin sensitivity Change from baseline to 6 weeks Insulin sensitivity calculated via the Matsuda Index during an oral glucose tolerance test
- Secondary Outcome Measures
Name Time Method Change in vastus lateralis muscle thickness Change from baseline to 6 weeks Muscle thickness of the vastus lateralis muscle measured via ultrasound
Change in whole body lean mass Change from baseline to 6 weeks whole body lean mass measured via bio-electrical impedance
Change in whole body fat mass Change from baseline to 6 weeks whole body fat mass measured via bio-electrical impedance
Change in one-repetition maximum muscle strength Change from baseline to 6 weeks Sum of one-repetition maximum of Bench press, biceps curl, lat pull down, overhead press, lateral raise, leg extension, leg curl and calf raise exercise
Change in knee extensor maximal isometric torque Change from baseline to 6 weeks Knee extensor maximal isometric torque measured during a maximal voluntary contraction
Change in grip strength Change from baseline to 6 weeks Grip strength measured with a hand held dynamometer
Change in mean glucose levels Change from baseline to 6 weeks Mean glucose levels measured via continuous glucose monitors
Change in glucose variability Change from baseline to 6 weeks Glucose variability measured via continuous glucose monitors
Trial Locations
- Locations (1)
Stuart Robert Gray
🇬🇧Glasgow, United Kingdom