Metabolic effects of morning light.
Completed
- Conditions
- glucose metabolism
- Registration Number
- NL-OMON25124
- Lead Sponsor
- Academic Medical Center (AMC), Department of Endocrinology and Metabolism
- Brief Summary
Versteeg RI, Stenvers DJ, Visintainer D, Linnenbank A, Tanck MW, Zwanenburg G, Smilde AK, Fliers E, Kalsbeek A, Serlie MJ, la Fleur SE, Bisschop PH. Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes. J Biol Rhythms. 2017 Apr;32(2):130-142. doi: 10.1177/0748730417693480. Epub 2017 Mar 20. PubMed PMID: 28470119; PubMed Central PMCID: PMC5423535.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 8
Inclusion Criteria
1. Age 18-55 years;
2. Male sex;
Exclusion Criteria
1. Medication interfering with glucose metabolism or neuronal synaptic transmission;
2. Gastro-intestinal or metabolic disease that will interfere with digestion or metabolism;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To investigate the effect of morning light exposure on postprandial glucose excursions and expression of metabolic and clock genes in adipose tissue. <br>
- Secondary Outcome Measures
Name Time Method To investigate the effect of morning light exposure on postprandial insulin excursions, postprandial free fatty acid (FFA) excursions, postprandial triglyceride levels, morning glucocorticoid increase, morning salivary melatonin decrease and measurements of skin temperature decrease and heart rate variability.