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Clinical Trials/NCT06824571
NCT06824571CompletedNot Applicable

Effects of Taurine Supplementation on Repetitive Sprint Performance and Exhaustion Time in College Students Under High-Temperature and High-Humidity Conditions

Xiaodong Cheng1 site in 1 country16 target enrollmentStarted: December 1, 2024Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
16
Locations
1
Primary Endpoint
Change from Baseline in Peak Power (Watts)

Study Overview

Brief Summary

This study is designed to evaluate the effects of acute pre-exercise taurine supplementation at different doses on the performance of college students during exhaustive exercise and subsequent repetitive sprint (RS) activities in a high-temperature, high-humidity environment. Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups: high-dose taurine (6g), medium-dose taurine (4g), low-dose taurine (1g), and placebo. Key performance metrics such as peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump height, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE) will be measured.

The objective of this study is to assess how taurine supplementation influences exercise performance under these challenging environmental conditions. This study will help to better understand taurine's potential effects on exercise performance and contribute to nutritional strategies for athletes exposed to extreme conditions.

Detailed Description

This study is designed to evaluate the effects of taurine supplementation on exercise performance under extreme environmental conditions of high temperature and high humidity. The primary goal is to investigate whether taurine supplementation can enhance performance during exhaustive exercise and subsequent repetitive sprints (RS). Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups receiving either high-dose (6g), medium-dose (4g), low-dose (1g) taurine supplementation, or placebo.

The study will involve a protocol with exhaustive exercise followed by six repetitive sprints. Performance metrics such as peak power (PP), mean power (MP), and fatigue index (FI) will be recorded. Additionally, physiological parameters, including heart rate (HR) and blood lactate (BLA), as well as subjective measures like ratings of perceived exertion (RPE), will be monitored. A standardized measurement protocol will be used to ensure consistency and accuracy across trials.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Basic Science
Masking
Single (Participant)

Masking Description

The study employed a single-blind design where participants were masked to the intervention assignments. This means that participants were unaware of whether they received high-dose taurine (6g), medium-dose taurine (4g), low-dose taurine (1g), or placebo. The care providers and investigators were aware of the intervention assignments to ensure proper administration and data collection.

Eligibility Criteria

Ages
20 Days to 26 Days (Child)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • School students
  • Aged between 18 and 28 years
  • No exercise-related risk, as indicated by a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
  • No taurine-based supplements consumed in the last month.

Exclusion Criteria

  • Individuals who do not meet the inclusion criteria
  • Individuals with a history of cardiovascular issues, respiratory problems, or any condition that may impair exercise performance
  • Participants who did not provide a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
  • Participants who consumed taurine-based supplements in the month preceding the study.

Outcomes

Primary Outcomes

Change from Baseline in Peak Power (Watts)

Time Frame: Measured at the end of each sprint on Day 1 and Day 7.

Description: Maximum power output during each of the 6 sprints, measured using a cycle ergometer. Method of Assessment: Power output will be recorded for each sprint, and the peak value will be identified.

Change from Baseline in Mean Power (Watts)

Time Frame: Measured after all 6 sprints on Day 1 and Day 7.

Description: Average power output across all 6 sprints, reflecting sustained anaerobic performance. Method of Assessment: Power output will be averaged across all sprints.

Change from Baseline in Fatigue Index (%/s)

Time Frame: Measured across all 6 sprints on Day 1 and Day 7.

Description: Rate of decline in power output across the sprints, representing fatigue resistance. Method of Assessment: The decline in power output will be calculated as the difference between the first and last sprint, divided by the time interval.

Change from Baseline in Exhaustion Time (seconds or minutes)

Time Frame: Measured at the point of exhaustion during exhaustive exercise on Day 1 and Day 7.

Description: The duration participants can sustain exercise before reaching volitional exhaustion. Method of Assessment: Time will be recorded from the start of exercise until the participant reaches exhaustion.

Change from Baseline in Blood Lactate Levels (mmol/L)

Time Frame: Measured at baseline (pre-exercise), immediately after exercise, and at specific recovery intervals on Day 1 and Day 7.

Description: Blood lactate levels will be measured to evaluate metabolic stress and recovery during exercise. Method of Assessment: Blood samples will be collected at designated time points during recovery to assess lactate accumulation and clearance.

Secondary Outcomes

  • Change from Baseline in Ratings of Perceived Exertion (RPE)(Measured continuously during exhaustive exercise and repetitive sprint activity on Day 1 and Day 7.)

Investigators

Sponsor
Xiaodong Cheng
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Xiaodong Cheng

Xian Medical University

Xi'an Medical University

Study Sites (1)

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