A clinical trial to study the effect of a drug,Taurine in Subjects having traumatic Spinal cord INJURY
- Conditions
- Health Condition 1: G89-G99- Other disorders of the nervous systemHealth Condition 2: G89-G99- Other disorders of the nervous system
- Registration Number
- CTRI/2022/11/047262
- Lead Sponsor
- King georges medical university,Department of Orhopaedic Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion criteria for controls
Age and sex matched healthy controls were amongst the attendants of the ASCI subjects, having no known pathology and gave their consent to participate in the study.
Inclusion criterion for ASCI subjects
1. Age 18 - 65 years of either gender,
2. ASCI <3 weeks of injury
3. Complete motor injury (AIS-A, B)
Exclusion criterion for ASCI subjects
1.Other associated injuries such as major thoracoabdominal injuries & head injuries needing intervention.
2.Neuro-psychiatric patients and patients on steroid or other immunosuppressant therapy or other comorbid conditions making subjects unfit for surgery.
3.Subjects with non-vegetarian diet.
4.Subjects who do not give consent for participating in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Taurine supplementation improves; AIS Scale, Sensory- Motor and SCIM and SF-36scores following in ASCI subjects.Taurine supplementation promotes Neurological Recovery.Timepoint: During Admission,3rd Week,3rd month,6th Month.
- Secondary Outcome Measures
Name Time Method Taurine supplementation improves; AIS Scale, Sensory- Motor and SCIM and SF-36 scores following in ASCI subjects, other none targeted metabolites which are exceeding that variable importance on projection (VIP) scores greater than taurine then they will also be considered in this study.Timepoint: 8 month,12 month,24 month.