Reduction of antibiotic therapy by biomarkers in patients with CAP episodes - REDUCE study

Medisch Centrum Alkmaar0 个研究点目标入组 468 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Male and female patients with a diagnosis of CAP and all criteria listed below:
•1. Age 18 or above, no upper age limit will be employed.
•2. Patients must require hospitalisation.
•3. Clinical presentation of an acute illness with one or more of the following symptoms:
•a. Temperature * 38.0 *C (100.4°F)
•b. Dyspnoea
•c. Cough (with or without expectoration of sputum)
•d. Chest pain
•e. Hemoptysis
•f. Malaise or fatigue
•h. Gastro-intestinal symptoms
•i. Rales, rhonchi or wheezing
•j. Egophony or bronchial breath sounds
•4. New consolidation(s) on the chest radiograph.
•5. Written informed consent obtained.
•6. (Pre-event) Life expectancy > 30 days.

•Subjects presenting with any of the following will not be included in the study:
•1. Severe immunosuppression (HIV infection, chemotherapy).
•2. Active neoplastic disease.
•3. Obstruction pneumonia (e.g. from lung cancer).
•4. Aspiration pneumonia.
•5. Pneumonia that developed within 8 days after hospital discharge.
•6. Unable and/or unlikely to comprehend and/or follow the protocol.
•7. Pregnant and/or lactating women.

发起方

Medisch Centrum Alkmaar