The use of biomarkers to direct antibiotic and systemic corticosteroid therapy in chronic obstructive pulmonary disease (COPD) exacerbations: a randomised controlled study

niversity Hospitals of Leicester NHS Trust (UK)0 个研究点目标入组 106 人开始时间: 2009年7月30日最近更新: 2015年1月13日

试验速览

暂无简介。

•1. Provision of informed consent
•2. Male or female
•3. Aged 40 years or over
•4. Diagnosis of COPD
•5. Greater than one exacerbation requiring antibiotics and or corticosteroids in the preceding year

•1. Current active respiratory tuberculosis
•2. Upon questioning the patient known human immunodeficiency virus (HIV) infection or positive hepatitis B or C
•3. Known inability to produce a sputum sample during the induced sputum procedure
•4. Clinically relevant disease or disorder (past or present) which in the opinion of the investigator may either put the subject at risk because of participating in the study or may influence the results of the study or the subject's ability to participate in the study
•5. Any clinically relevant lung disease other than COPD
•6. Donation of blood within 3 months or during the study (for other than study purpose)
•7. Pregnancy or lactation

发起方

niversity Hospitals of Leicester NHS Trust (UK)