â??Effect of Yoga on Cardiovascular & Biochemical parameters in Prediabetes

Phase 1

Conditions: Health Condition 1: null- prediabetes

Registration Number: CTRI/2017/06/008825

Lead Sponsor: RUHS college of medical sciences jaipur

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 250

Inclusion Criteria

1.Ambulatory participants aged 30 to 50years

2.All subjects with Fasting blood glucose level of: 110 to 125 mg/dL (6.1 mM/L to 6.9 mM/L) & Two hour glucose tolerance test , blood sugar level of 140 to 199 mg/dL (7.8 to 11.0 mM) ,hemoglobin A1c (HbA1c) levels 5.5% to 6.5% any of the above two parameters will include .

3.no personal history of cardiovascular disease, no cardiovascular disease in the first-degree relatives, and serious illness requiring admission to hospital in the past year

Exclusion Criteria

1.Fasting blood glucose < 100mg/dl & >126 mg/dl , OGTT < 140 & >200 mg/dl glycated hemoglobin < 5.5% & > 6.5% systolic blood pressure >= 160 mmhg or diastolic blood pressure >= 100 mmhg

2. Abnormal liver function test (alanine aminotransferÂ¬ase [ALT] or aspartate aminotransferase [AST] >= 2.5-fold the upper normal limit

3. Alcoholic individuals (weekly alcohol consumption >= 140 g).

4. Renal dysfunction, diabetic retinopathy and neuropathy and any other major complications.

5.Those being treated with steroid or non-steroidal anti-inflammatory medication

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
4.Practice of comprehensive yogic breathing had beneficial effects on cardiac autonomic functions in prediabetes. Since cardiac dysfunction has been implicated in sudden cardiac death in diabetes, this finding may translate to practice of yogic breathing program being useful in delaying sudden cardiac death.Timepoint: two year

Secondary Outcome Measures

Name	Time	Method
6. Studies has been established practice of comprehensive yogic breathing program significantly improves physical, psychological, and social domains, and total quality of life. In view of the existing knowledge and yoga being a cost â??effective technique without side effects, it appears appropriate to incorporate yoga/meditation for primary and secondary prevention of cardiovascular disease.Timepoint: 2 years