A double-blind randomized controlled trial of ''Qin-Re Li-Shi Tong-Luo'' approach in the treatment of Acute gouty arthritis
- Conditions
- Gout
- Registration Number
- ITMCTR2000003719
- Lead Sponsor
- Yueyang Integrated traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Those who meet the diagnostic criteria of Western medicine for gouty arthritis and the diagnostic criteria of TCM syndromes;
(2) Between 18-70 years old, male or female;
(3) The acute attack was within 48 hours, and the baseline assessment showed that the total score of pain, tenderness and swelling was >= 5;
(4) No non-steroidal anti-inflammatory drugs or drugs affecting uric acid metabolism were taken within one week before the observation;
(5) Understand and agree to participate in this study and sign an informed consent form.
(1) Acute multi-joint gout involving more than 4 joints
(2) complicated with osteoarthritis, rheumatoid arthritis and other arthritis diseases
(3) Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system, and mental illness;
(4) patients with active gastrointestinal diseases and patients with digestive tract ulcers in the first 30 days of this study;
(5) Those who are in critical condition and are difficult to make an accurate assessment of the effectiveness and safety of this clinical observation;
(6) Those with severe deformity, stiffness, and loss of labor due to advanced arthritis;
(7) Those who are known to be allergic to the drug used in this study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VAS score;Safety and Tolerability of Polygonum Cuspidatum Gout Granules;
- Secondary Outcome Measures
Name Time Method Researcher's overall evaluation of treatment response;Joint swelling (0-3 point scale);Patient's overall evaluation of response to treatment;Joint tenderness (0-3 point scale);