Clinical trial comparing the effectiveness of intraperitoneal bupivacaine, acetazolamide and placebo on pain relief after laparoscopic cholecystectomy surgery
Not Applicable
- Conditions
- Calculus of gallbladder without cholecystitis.Cholecystolithiasis Cholelithiasis Colic (recurrent) of gallbladder Gallstone (impacted) of: cystic duct gallbladder unspecified or without cholecystitis
- Registration Number
- IRCT2017032733159N1
- Lead Sponsor
- Vice Chancellor for research of Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
having physical status I or II of the ASA system (American Society of Anesthesiologists); aged 20 to 60 years; who were candidate for laparoscopic cholecystectomy surgery due to gallstone.
Exclusion criteria: Patients who do not consent to be included in the study; bile duct problems; acute cholecystitis; lack of ability to understand and use visual analogue scale (VAS); experience of sensitivity to NSAIDs and local anesthetics; class III and IV of ASA system; patients with choledocolitiasis; and drain in situ.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: visual analog scale.;Paracetamol usage. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: according to patient documents.
- Secondary Outcome Measures
Name Time Method Heart rate. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: documentd by doctor.;Systolic blood pressure. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: documentd by doctor.;Diastolic blood pressure. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: documentd by doctor.;Respiratory rate. Timepoint: just after surgery then 1, 4, 8, 12, and 24 hour after that. Method of measurement: documentd by doctor.