NCT00225745已完成不适用
Assessment of Plasma Ghrelin Levels in Patients With Pancreatic Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- To evaluate plasma ghrelin levels in patients with pancreatic cancer and compare with age matched controls
研究概览
简要总结
The primary outcome measure for this study is plasma ghrelin level.
详细描述
The primary outcome measure for this study is plasma ghrelin level, and the two primary comparison are:
- Patients with cachexia versus patients without cachexia
- Patients with cachexia versus healthy controls
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Histological or cytological proof of pancreatic adenocarcinoma
- •The control are will include healthy age-matched patients without cancer
- •The test arm will include patients with pancreatic cancer and they will divided into two groups: those with and without weight loss
- •Patients must have recovered from any major infections and/or surgical procedures
排除标准
- •Patients with other serious medical illness like congestive heart failure, thyroid disease,liver disease or renal failure - conditions that will alter their nutritional state
- •Patients on appetite stimulant and those receiving total parenteral nutrition
- •Patients who have undergone gastrectomy or those who have gastric ulcers
- •Patients receiving active chemotherapy
- •No prior malignancy except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer or for which patient has been disease free for at least five years.
结局指标
主要结局
To evaluate plasma ghrelin levels in patients with pancreatic cancer and compare with age matched controls
时间窗: prior to treatment
次要结局
- To investigate the role of ghrelin in pathophysiology of cancer cachexia(prior to treatment)
- To generate hypotheses for future studies and treatment based on the findings(prior to treatment)
研究者
研究点 (1)
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