The Correlation Between HbA1c and Mean Blood Glucose in Patients With Diabetes and Renal Failure

Terminated

• Conditions: Renal Failure; Diabetes

• Registration Number: NCT01937858
• Lead Sponsor: Reem Mohammad Alamoudi

Brief Summary

The value of HbA1c as a tool to determine glycemic control in patients with diabetes and renal failure has not been well studied, the same accepted normal ranges for HbA1c are applied to all patients with diabetes regardless of their renal function. We would like to evaluate the use of HbA1c as a tool of assessing long term glycemic control in this subgroup of patients with diabetes and evaluate the effect of dialysis on HbA1c

Detailed Description

Not available

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2013-09-04
• Study First Submitted QC: 2013-09-04
• Study First Posted: 2013-09-10
• Primary Completion: 2016-03
• Study Completion: 2016-07
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-19
• Last Update Posted: 2020-02-20

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

All patients >18 years of age with type 1 or 2 diabetes who show competence in home glucose monitoring and are willing to commit to doing the testing

Exclusion Criteria

• Pregnancy
• Having received a blood transfusion with in the preceding three months
• Known to have any hereditary or hemolytic anemia
• On a medication known to interfere with HbA1c assay (opiates, acetaminophen, vitamin C, vitamin E) - we will allow patients to be on asprin as almost all patients with diabetes are on this drug.
• Having a blood hemoglobin <7 mg/dl
• Bilirubin level >20mg/dL or a triglyceride level > 250mg/dL
• Alcohol addiction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation	three months	The quantitative correlation between mean blood glucose and HbA1c in patients with diabetes and renal failure