Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults

Not Applicable

Completed

• Conditions: Resting Energy Expenditure
• Interventions: Other: Respiratory analysis at cold temperature; Other: Respiratory analysis at room temperature; Other: Respiratory analysis at thermoneutral temperature; Other: Respiratory analysis at hot temperature

• Registration Number: NCT05505240
• Lead Sponsor: University of Bonn

Brief Summary

The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.

Detailed Description

In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.

Study Timeline

• Study First Submitted: 2022-08-15
• Study First Submitted QC: 2022-08-15
• Study First Posted: 2022-08-17
• Study Start: 2022-11-21
• Status Verified: 2023-04
• Primary Completion: 2023-04-06
• Study Completion: 2023-04-06
• Last Update Submitted: 2023-04-11
• Last Update Posted: 2023-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Cold temperature	Respiratory analysis at cold temperature	18°C
Room temperature	Respiratory analysis at room temperature	22°C
Thermoneutral temperature	Respiratory analysis at thermoneutral temperature	28°C
Hot temperature	Respiratory analysis at hot temperature	38°C

Primary Outcome Measures

Name	Time	Method
Resting Energy Expenditure	20 minutes	Volume of inhaled oxygen (VO2) in L/min and exhaled carbon dioxide (VCO2) in L/min

Secondary Outcome Measures

Name	Time	Method
Body surface temperature	20 minutes	Body surface temperature: assessed every ten seconds during respiratory analysis (°C)
Body core temperature	20 minutes	Body core temperature: assessed every ten seconds during respiratory analysis (°C)
Body composition	5 minutes (after respiratory analysis)	assessed daily via bioelectrical impedance analysis after respiratory analysis (FFM (kg), FM (kg))
Blood pressure	10 minutes (at beginning of study day)	assessed daily before respiratory analysis (mmHg)

Trial Locations

Locations (1)

University of Bonn; 🇩🇪 Bonn, Germany